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Sunday, January 5, 2014

Do You Believe in Magic?: The Sense and Nonsense of Alternative Medicine.

By Paul A. Offit

            Dr. Offit has received a great deal of attention for his books, especially those concerned with vaccines and their potential link to autism.  He certainly has an excellent pedigree (Professor of Vaccinology, Pediatrics, Chief of the Division of Infectious Diseases, Director of the Vaccine Education Center, member of the Centers for Disease Control (CDC) to name a few) and has shared his vast knowledge in this book.  This book examines all forms of alternative medicine from chiropractic care, traditional Chinese medicine and acupuncture, to homeopathic treatment. 

One of the first points that Offit makes is that there really is no such thing as alternative medicine.  Webster’s dictionary defines “medicine” as a substance that is used in treating disease or relieving pain.  Simply put, a substance either does or does not achieve this goal.  Offit shares several stories of people who opted for alternative treatments, when traditional medicine would have offered a greater chance of survival.  At seven years of age, Joey Hofbauer was diagnosed with Hodgkin’s disease, a cancer of the lymph glands.  Instead of opting for traditional treatment involving chemotherapy, Joey’s parents opted to treat his cancer with Laetrile, and a specialized diet consisting of raw milk, coffee enemas, an “autogenous vaccine” (made from bacteria in his own urine), and massive doses of vitamins.  This controversial treatment almost immediately cast Joey’s family into the spotlight scrutinizing how Joey should be treated.  Initially, Joey had one swollen lymph gland.  After 6 months of unconventional treatment, he had 17 and liver damage from overdosing on vitamin A.  In July of 1980, with lungs riddled with tumors, Joey succumbed to the cancer.  During this three year legal battle, these controversial treatments were studied for efficacy, not a one proved to be an effective treatment for cancer.

Question:  Are vitamins good for you?  What about antioxidants?  Unfortunately the answer might not be as simple as we’d like it to be.  The “antioxidant paradox” is a term coined by researchers who have theorized that massive doses of antioxidants can shift the balance between free radical production and destruction, resulting in an unnatural state which causes the immune system to be deficient in killing harmful invaders.  He also cites several studies which have examined the effect of vitamins on health.  A study of 29,000 long-term smoking Finnish men who took vitamin E, and/or beta-carotene (or the control group with no supplementation) indicated that those taking the supplements were MORE likely to die from lung cancer or heart disease than those who did not.  Men who take a multivitamin were twice as likely to die from advanced prostate cancer, according to a study of 11,000 men by the National Cancer Institute.  More examples are cited, but I think the point is clear.
           
            Overall, this book identifies some crucial questions that must be examined as we think about how we treat diseases, and more importantly how we treat the people.  The placebo effect works, as indicated by numerous studies, but when is it appropriate?  Endorphins released due to acupuncture can help with pain, but acupuncture will do nothing for cancer.  In fact, Chinese medicine was developed by “physicians” who were not allowed to dissect the human body.  Their foundation for healing is based on an application of observable outside events to the human body.  The twelve meridians of the body were chosen for the 12 great rivers in China, and the number of acupuncture points (~360) was determined by the number of days in the year.  The key really is that we need to test “alternative medicine” in the same way that we test traditional medicine.  “There is no such thing as alternative medicine, but rather medicine that works and medicine that doesn’t.”  Alternative medicine has dodged testing thus far by painting the FDA and pharmaceutical companies as the bad guy.  This has nothing to do with cutting into a pharmaceutical company’s profits, and more to do with the safety of product.  Drugs require rigorous testing to assure there are no potentially dangerous degradation products, solvents, or dangerous metals and adulterants present.  These natural treatments should not only require testing to prove efficacy, but also to assure they meet the rigorous standards that are required in the pharmaceutical industry. 

Beware of the celebrity endorsements, just because they have the spotlight doesn’t mean that they know what’s best for us.  Jenny McCarthy doesn’t know shit about vaccines, Steve Jobs might still be alive if he treated his cancer with surgery instead of acupuncture and herbal remedies, Suzanne Somers was a ditzy television star – not a medical doctor.  She understands little about medicine, encouraging growth hormone and estrogen therapy for her followers.  Apparently because she is supplementing with “natural bioidentical hormones” from plants, we don’t need to be concerned about the numerous studies the NIH has conducted linking estrogen therapy with an increase in breast cancer.  Certainly plants (often used in herbal/holistic remedies) contain chemicals which can be used to treat diseases.  There is a whole branch of chemistry based on the synthesis of compounds found in plants (I used to be involved in natural product synthesis).  Yet, after synthesizing, these compounds require years of testing by the FDA, which can cost millions of dollars.  So why should we assume that plants containing chemicals in holistic treatments should be excluded from testing?  There’s a reason we test therapies like we do, to assure that they work. 

We can’t deny the comfort that many find in the world of alternative medicine.  Modern medicine is in a state of flux because of increased information, which can be unnerving.  Nobody wants to hear that their disease is so new, that we have no sure way of treating it and must make our best guess.  Alternative medicine offers a degree of comfort that modern medicine cannot; this therapy has been the same for 5,000 years.  The placebo effect can be powerful in cases where treatment is not crucial.  I can’t offer a better summary than the author did, so I will include it here:

The problem comes when mainstream healers dismiss the placebo response as trivial or when alternative healers offer placebos instead of lifesaving medicines or charge an exorbitant price for their remedies or promote therapies as harmless when they’re not or encourage magical thinking and scientific denialism at a time when we can least afford it.

Rating: 4.25 out of 5 Bunsen Burners

Up Next: any of 3 Chuck Palahniuk books, 2 Orson Scott Card books (speaker for the dead and Xenocide), or Mystic River.  Also, I got a Kindle for Christmas and have a ton of books on it to read.  I have a feeling my life will never be the same.

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